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Free Ebook Translational Medicine: Molecular Pharmacology and Drug Discovery (Current Topics from the Encyclopedia of Molecular Cell Biology and Molecular Medicine)

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Translational Medicine: Molecular Pharmacology and Drug Discovery (Current Topics from the Encyclopedia of Molecular Cell Biology and Molecular Medicine)

Free Ebook Translational Medicine: Molecular Pharmacology and Drug Discovery (Current Topics from the Encyclopedia of Molecular Cell Biology and Molecular Medicine)

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About the Author

Robert A. Meyers obtained his Ph.D. in Chemistry at the University of California at Los Angeles. He was a post-doctoral fellow at the California Institute of Technology and has more than 17 patents, 50 technical papers and 12 books to his name. As Editor-in-Chief he conceived and edited several ambitious multivolume reference works, e.g. the Encyclopedia of Analytical Chemistry (Wiley), the Encyclopedia of Molecular Biology and Molecular Medicine (Wiley-VCH) and the Encyclopedia of Physical Science and Technology (Academic Press).

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Product details

Series: Current Topics from the Encyclopedia of Molecular Cell Biology and Molecular Medicine (Book 2)

Hardcover: 1064 pages

Publisher: Wiley-Blackwell; 1 edition (July 16, 2018)

Language: English

ISBN-10: 9783527336593

ISBN-13: 978-3527336593

ASIN: 3527336591

Product Dimensions:

7 x 2.2 x 9.9 inches

Shipping Weight: 5 pounds (View shipping rates and policies)

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Amazon Best Sellers Rank:

#3,360,263 in Books (See Top 100 in Books)

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Translational Medicine: Molecular Pharmacology and Drug Discovery (Current Topics from the Encyclopedia of Molecular Cell Biology and Molecular Medicine) PDF

Ebook The Island of Knowledge: The Limits of Science and the Search for Meaning

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The Island of Knowledge: The Limits of Science and the Search for Meaning

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Listening Length: 10 hours and 33 minutes

Program Type: Audiobook

Version: Unabridged

Publisher: Audible Studios

Audible.com Release Date: February 11, 2015

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This book is ostensibly about the inherent limits of scientific knowledge, but actually provides an excellent summary of what is known (at least in physics) and traces its development from the Greeks onward, in the process of identifying these limits. One limit arises from the cosmic horizon of 13.8 billion years, before which the universe was opaque to radiation, implying that we can never receive information about regions further away than 13.8 billion light-years. Uncertainity at the sub-microsopic scale is due to the quantum weirdness of knowing only the probability of a particles's location until it is measured, the inherent uncertainty of that measurement and the entanglement (action at a distance) between particles Early Western philosophers looked for a unified theory of the nature of matter. Thales (600 BCE) thought "all stuffs of the world were but different manifestations of a primal stuff, the embodiment of a reality always in flux". Parmenides, somewhat later, wrote "that what is can not change, for it then becomes what it is not". According to Lucretius (50 BCE), Leucippus and Democritus thought that all things were made of unchanging atoms moving in a void under various forces, assuming different shapes and forms under different forces by the reordering of numerous atoms. Aristotle posited a bottom-up natural arrangement of his four basic substances--earth, water, air and fire--to explain why a body moved up or down when displaced from its natural place. As the author notes, scientific inquiry is an ongoing process, implying an ever-changing perception of reality. Aristotle's version of physical reality dominated western thought until Galileo, Kepler and Newton in the 17th century turned to measurement of physical phenomena and the construction of natural laws to explain those measurements, thereby constructing a new version of physical reality which was embellished over the next two centuries, notably by Maxwell's introduction of the electromagnetic field. Then, early in the 20th century this classical version of physical reality was shattered by Einstein's replacement of Newton's force-at-a-distance concept of gravity by the warping of space, and the quantum theory of Heisenberg and Schrodinger raised issues of how to understand the fundamental laws that govern physical reality. The author provides an enlightening discussion of the many fascinating aspects of 20th century physics, from which he concludes that there may be inherent limits to what science (physics) can say about physical reality, and these limits are more than just limitations in technology. Many physicists, myself included, would stop short of this conclusion, noting the author's earlier statement that scientific inquiry is an ongoing process, implying an ever-changing perception of reality.

Providing an overall reflective survey of mankind's incremental probing and discernment of physical reality, this book is remarkably readable for motivated non-scientists. It is generally well composed, and the text and ideas both flow smoothly and plausibly. Moreover, this book engenders a sustained if not escalating sense of awe regarding the evolved state of knowledge of the physical sciences, together with an appreciation of the enormity of its enabling contributions.Regarding the book's title, the expanding island/shoreline metaphor is apt and well elaborated. Here the area of the island associates with the body of extant knowledge, and the shoreline with the accumulation of unanswered questions. From the shoreline, the waters loom as the unknown, and even some of the unknowable, against the horizon of the marginally knowable. Beyond the horizon lies the strictly unknowable, as proscribed via physical constraints. Notably, the island of knowledge is not composed solely of scientific knowledge, as the author admits other ways of knowing (which lie outside the scope of the book). Plato's Allegory of the Cave is also invoked to characterize human limitations in discerning reality. As an interesting twist, the cave wall, onto which human access to reality is projected, affords enhanced perceptual resolution concomitant with the increase in extant knowledge.The book is divided into three complementary parts: the cosmos, matter, and cognitive faculties. I found the first two parts to be excellent and most insightful, but the third part seemed rather weak and not well integrated into the foregoing parts. Seemingly, the book's treatment of cognitive faculties is directed at limitations regarding human prospects for dealing with the potentially knowable. Here, binding limitations associate with intellectual tools like mathematics, and constraints like those imposed by Godel's Proof. Thus, some cognitive limitations apply to scientific inquiry in general. Aside from these absolute limitations, each individual investigator has personal perceptual horizons that tend to occlude or distort the apprehension of what precisely is known, what is potentially knowable, and what questions are in consequence entailed or answerable. Apart from inherent limitations on what is knowable per considerations of physics then, there are cognitive limitations of either an essential nature or an incidental one.Furthermore, these three parts of the book do not reflect a "shifting scientific worldview" (p. xiv), at least in my construal; rather, these foci have been more or less contemporaneous since antiquity. Instead, the distinguishing shifts largely associate with the progression of four understandings of the phenomenon of gravity: Aristotelian, Newtonian, Einsteinian, and that of quantum gravity. This progression is quite well developed in the first two parts of the book. Moreover, this progression now yields to the prospect of a pending "new physics (that) needs to explain how...the physics of the very large meets the physics of the very small. This is the realm of `quantum gravity', the marriage of the general theory of relativity with quantum physics" (p. 72).What especially held my interest in the first two parts was the well integrated and highly readable exposition of the key controversies and discoveries in the physical sciences. The text read well and the ideas flowed smoothly. This coverage was augmented by relevant notes on shifting worldviews, contributions/speculations of principal figures, and the author's remarks/insights. Regarding worldview transitions, the current protracted puzzlement and dissensus with respect to the interpretation and full assimilation of quantum theory receive insightful treatment, albeit one necessarily with a less than satisfying closure. Basically, the radical yet demonstrated aspects of quantum physics of action-at-a-distance and quantum interference are deeply disquieting and obdurately problematic for many in the physical sciences research community. This demonstration is nicely described in Chapter 26, wherein the author undertakes to "discuss Bell's theorem and how its experimental implementation shows that reality is stranger than fiction." Here, the `extraordinary' prevails in several experimental cases, which show the violation of Bell's inequality in consonance with the quantum predictions.Accordingly, a still emerging worldview will somehow have to rationalize and accept "how nature behaves at the shortest distances", i.e., action nonlocality and measurement nondeterminism. In consequence, there is now major research emphasis on the foundations of quantum physics, as in the phenomena of pair entanglement and superluminal interactions. Meanwhile, derivative technologies like semiconductor devices and quantum computing are nonetheless exploiting quantum effects, if only on an as yet exploratory basis.Among the interesting sidelights regarding the actual research pursuits of quite a few historically prominent figures are their somewhat prevalent investigations into alchemy or the occult. Newton, for example, was considerably involved in alchemy, and J. J. Thompson in occult endeavors. Alchemy, moreover, is seen as sort of a precursor to modern science, although it eventually discarded such subject matters. With the demonstration of quantum weirdness or the `extraordinary', however, it would seem that such discarding may not be altogether warranted, at least rhetorically.As a non-specialist in its subject areas, I nonetheless really enjoyed this book. Its content was very illuminating, largely in that it clearly explained and integrated matters with which I had been somewhat familiar but inadequately informed. Despite certain of my reservations, like one cited above, I believe this book to be a solid Five-Star selection. Further, Professor Gleiser's writing would suggest that he is an agile, spellbinding, and compelling lecturer.

The author gives us an honest view of why our knowledge is limited and will remain so. He feels us that our search for understanding will expand our view of reality, but we cannot pitch our tent on the conquered territory because we are nomads in perennial search of new lands.I liked this book because it tells a credible story of what is possible for us. Understanding our limitations is the first step to understanding our possibilities.Marcelo Gleiser is a trustworthy guide to travel in uncharted lands.

A very accessible "state of the union"(or disunion) in Physics. Like many my math skills are embarrassingly weak but I do enjoy a good physics read. This book doesn't hit you with a ton of formulas, the analogies used to describe things such as Quantum Mechanics, Superposition, Entanglements, &c. were very well done making these oftentimes difficult to understand concepts understandable. If you are looking for a page turner that attempts to bring you up to speed with the current effort to unify the laws of the very large and the very small you will be pleased with this book. Anyone reading at a high school level will find this book easy to understand and fascinating.

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Ebook , by Emily Ansara Baines

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Product details

File Size: 875 KB

Print Length: 256 pages

Publisher: Adams Media (November 1, 2011)

Publication Date: November 1, 2011

Language: English

ASIN: B00631IB3I

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#753,056 Paid in Kindle Store (See Top 100 Paid in Kindle Store)

i'm a self described Bookworm Nerdgirl Fatkid which means I love to read, eat, and read cookbooks - SO the fact there is a Hunger Games "unofficial" cookbook, was one I couldnt pass up (plus the digital version was cheaper than the actual book)the recipes are pretty straight forward, simplified a lil here and there, making ingredients more easily attainable. its def a fun, kind of cheeky twist on a movie tie inalso a nice little touch is the commentary from the "sponsor" about several of the recipes :)I recommend this purchase for a future Hunger Games themed dinner party/movie nite!

This book was such a cute idea, that I had to have it. I'm a big fan of the Hunger Games series, so this cookbook was a fun addition to my kitchen. I didn't recognize all the recipes as pieces from the book, but I think that's because some are just 'inspired by' the series. The ones I've made so far are pretty tasty, and it makes having a HG themed party a snap, foodwise. I also bought this used, so I definitely don't regret the money spent- but, I bet a new copy (with non-bent edges and a clean front) would be an even greater addition to a collection.

Some of the best recipes I have ever made... it also makes me feel like I am sending a parcel into the games.

The girl I gave it to loved it so much, it was the perfect gift!

came in the mail tonight, i love it! simple as that. i actually made three items from the cookbook, and they we're amazing!! omg so good. i had the pink mashed pos, with a grilled stuffed groosling, and chai lette. it was wonderful, having a birthday party, and making some of the food out of the book, i'd also like to remind any silly parents that buy this from their "hg super fan" child. it's not for kids, it's more for 16 and up! not 12 to 15 it'll bore them and they'll get tired quite fast. i'm 18 and i love this book, it's wonderful. their's a few recpi's that call for "wild dog" it's a punt, lolololol. for anyone who gets mad over it should laugh their joking it says to use a red meat. c:

I bought this cookbook before our book club discussed "Hunger Games." We have a combined book discussion and potluck, so I shared recipes, and it was a lot of fun. Many were introduced to quinoa -- one warning: the recipe for quinoa and black bean salad says it serves 4 to 6, but after 8 hearty servings, we still have half left. I would cut the amount of quinoa in half for both the quinoa recipes -- 1-1/2 cups makes quite a lot.

Wish this had some pictures or visual interest of some kind. I like my cookbooks a little more aesthetically engaging.

My son ordered this as a gift for his girlfriend. The shipping was super-quick and it's a nice looking book. I flipped through it, and it seems like a ton of recipes that no one will ever use, especially the teens that it's (I assume?) marketed toward. Rabbit? Really? Anyway, if you have a teen girl in your life who is crazy about Hunger Games and enjoys cooking, maybe she'll like this book. I sure hope so!

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